Tuesday, June 12, 2012

Cancer Causes Death...But It's Not What You Think


            Obviously cancer is deadly.  It is a disease that attacks the cells in our body and creates mutations that make its own cells immortal, but is dying from cancer the only worry that cancer patients should have?  Based on the article, Non-cancer mortality among people diagnosed with cancer, we see a trend in the deaths of cancer patients versus non-cancer patients, and notice that the higher death rate among people with cancer is not always necessarily due to cancer.  So why do cancer patients have a much higher chance of dying from a non-cancer related mortality?  What does this say about lifestyles, health related issues, and even psychological aspects of the disease?



            In this study, done in Queensland, Australia, Peter Baade, Lin Fritschi, and Elizabeth Eakin examine and compare death records of cancer patients and a control group without cancer, to study how and why they died.  The results were astounding, showing that compared to the general non-cancer population, cancer patients were 50% more likely to die of non-cancer causes.  To find these statistics, only non-cancer causes of death with at least 100 deaths over the period of the study were used.  To consider a death to be non-cancer related, it must not be directly related to cancer treatment (such as dying during surgery) but could be indirectly related to a type of treatment based on its long-term effects.  The types of cancer that had the most noticeable mortality rates also differed greatly.  Breast cancer and melanoma patients did not differ significantly from the general population, but people with lung cancer had the highest rate of non-cancer related deaths.


            There are multiple theories as to why cancer patients have a higher rate of non-cancer related fatalities, but they aren’t necessarily mutually exclusive.  The first is the side effects of cancer treatments (again, only indirectly related treatment options would be counted) could cause another condition.  Second could be that instead of cancer leading to another condition, a patient with a non-cancer condition could get extensive and invasive testing involving the diagnosis and treatment, which then leads to the subsequent diagnosis of cancer.  Third could be the representativeness of the general population in the cancer population.  It is shown that cancers with the lowest death rate such as breast cancer and melanoma are associated with a very affluent population in Australia, giving them the means to get effective treatment options.  Fourth is that the factors that cause cancer could also be the same factors that cause the non-cancer related death.  Cigarette smoke causes lung cancer (associated with the highest rate of non-cancer deaths), but is also responsible for other deadly conditions such as heart disease, pulmonary disease, and stroke.  This seems like one of the most likely reasons for the increased death rate in cancer patients because of the many factors that can cause cancer.
            One other factor that I would have liked to look at in this study would be the psychological effects that cancer patients have, which could also lead to other forms of death.  It is shown that people with increased happiness and a higher self-evaluated quality of life could possibly live longer than those with a bleak outlook.  This could confirm why cancer patients have a larger overall non-cancer death rate, if there is a chance that diagnosis gave them a more pessimistic view on life as well as why those cancers with a high survival rate such as breast cancer and melanoma, also have a decreased non-cancer death rate.  In addition, the figure shows the rate of suicide, possibly correlating with this psychological aspect.  The rate is low for high-survival cancers but high for low-survival rate ones such as lung cancer.